JOEM: Influence of Shift Work on Arterial Stiffness (April 2023)-JOEM: Influence of Shift Work on Arterial Stiffness (April 2023)

JOEM: Influence of Shift Work on Arterial Stiffness (April 2023)

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The study investigated the influence of shift work on arterial stiffness and systemic inflammation among industrial workers. A total of 86 participants, including 57 shift workers and 29 day workers, were followed up over a period of 3 years. The researchers collected demographic information, measured various cardiovascular disease risk factors, and assessed blood samples for markers of inflammation. <br /><br />At baseline, adhesion molecules soluble vascular cell adhesion molecule 1 (sVCAM-1) and soluble P-selectin were elevated among shift workers compared to day workers. Over the follow-up period, there was a significant difference in the change in pulse wave velocity (PWV) between the two groups, with shift workers experiencing a greater increase in PWV compared to day workers. PWV is an indicator of arterial stiffness and increased PWV is associated with increased risk for cardiovascular disease. However, there were no significant differences between the groups in changes in blood pressure, carotid media thickness, lipids, glycosylated hemoglobin, or other inflammatory markers.<br /><br />The findings suggest that shift work in the industry is associated with increased arterial stiffness, potentially increasing the risk for future cardiovascular disease. There was also some support for the presence of systemic inflammation among shift workers. However, the dust levels and particle sizes at the workplace were not considered hazardous to cardiovascular health. The study highlights the importance of organizing shift work in a way that minimizes the adverse effects on cardiovascular health. Further research is needed to explore the long-term effects of shift work on cardiovascular outcomes.

Keywords

shift work

arterial stiffness

systemic inflammation

industrial workers

cardiovascular disease

adhesion molecules

pulse wave velocity

blood pressure

carotid media thickness

inflammatory markers